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1.
Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness.
Cell
; 183(2): 335-346.e13, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33035452
2.
Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2.
J Pharmacol Exp Ther
; 376(3): 358-373, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33468641
3.
Design, Synthesis and Biological Evaluation of Oxindole-Based Chalcones as Small-Molecule Inhibitors of Melanogenic Tyrosinase.
Chem Pharm Bull (Tokyo)
; 65(9): 833-839, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28867710
4.
Recent developments in chimeric NSAIDs as safer anti-inflammatory agents.
Med Res Rev
; 35(2): 341-407, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25319808
5.
Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents.
Bioorg Med Chem Lett
; 25(22): 5281-5, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26428872
6.
Synthesis of lantadene analogs with marked in vitro inhibition of lung adenocarcinoma and TNF-α induced nuclear factor-kappa B (NF-κB) activation.
Bioorg Med Chem Lett
; 24(16): 3814-8, 2014 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25027934
7.
The Role of Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis: Identification of Signaling Pathways, Regulators, Molecular Interaction Networks, and Biological Functions through Bioinformatics.
Brain Sci
; 13(1)2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36672132
8.
Truncation or proteolysis of α-synuclein in Parkinsonism.
Ageing Res Rev
; 90: 101978, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37286088
9.
Ingenuity pathway analysis of α-synuclein predicts potential signaling pathways, network molecules, biological functions, and its role in neurological diseases.
Front Mol Neurosci
; 15: 1029682, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36523604
10.
(+)-Cyanidan-3-ol inhibits epidermoid squamous cell carcinoma growth via inhibiting AKT/mTOR signaling through modulating CIP2A-PP2A axis.
Phytomedicine
; 101: 154116, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35525235
11.
Bioinformatic Analyses of Canonical Pathways of TSPOAP1 and its Roles in Human Diseases.
Front Mol Biosci
; 8: 667947, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34212002
12.
Chiral HPLC separation of enantiomeric blebbistatin derivatives and racemization analysis in vertebrate tissues.
J Pharm Biomed Anal
; 204: 114246, 2021 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34271288
13.
Isolation optimisation, synthesis, molecular docking and in silico ADMET studies of lantadene a and its derivatives.
Nat Prod Res
; 35(21): 3939-3944, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32316769
14.
Recent Developments in Chimeric NSAIDs as Anticancer Agents: Teaching an Old Dog a New Trick.
Mini Rev Med Chem
; 16(15): 1201-1218, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27121716
15.
Novel lung adenocarcinoma and nuclear factor-kappa B (NF-κB) inhibitors: synthesis and evaluation of lantadene congeners.
Eur J Med Chem
; 74: 135-44, 2014 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24457265
16.
Topical (+)-catechin emulsified gel prevents DMBA/TPA-induced squamous cell carcinoma of the skin by modulating antioxidants and inflammatory biomarkers in BALB/c mice.
Food Funct
; 5(12): 3197-207, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25310126
17.
Novel dual inhibitors of nuclear factor-kappa B (NF-κB) and cyclooxygenase- 2 (COX-2): synthesis, in vitro anticancer activity and stability studies of lantadene-non steroidal anti-inflammatory drug (NSAID) conjugates.
Curr Top Med Chem
; 14(8): 991-1004, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24660685
18.
Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity.
Eur J Med Chem
; 80: 167-74, 2014 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24780593
19.
Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity.
Eur J Med Chem
; 66: 372-9, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23827177
20.
Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory, anticancer agents: design, synthesis and biological screening.
Eur J Med Chem
; 63: 589-602, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23548704
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